The contribution of placental histopathology in investigating adverse pregnancy outcome May 24, 2019

Why does adverse pregnancy outcome often remain unexplained?
There may be poor correlation between maternal indicators of infection and placental findings.
Placental causes of foetal and perinatal death may be clinically silent, e.g. delayed villous maturation or foetal vascular malperfusion (FVM).
Intrauterine growth restriction has a multifactorial aetiology related to foetal, maternal and placental pathology.

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